| Course Unit Code | 460-4100/01 |
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| Number of ECTS Credits Allocated | 4 ECTS credits |
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| Type of Course Unit * | Optional |
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| Level of Course Unit * | Second Cycle |
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| Year of Study * | Second Year |
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| Semester when the Course Unit is delivered | Winter Semester |
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| Mode of Delivery | Face-to-face |
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| Language of Instruction | Czech |
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| Prerequisites and Co-Requisites | Course succeeds to compulsory courses of previous semester |
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| Name of Lecturer(s) | Personal ID | Name |
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| VAS218 | Ing. Michal Vašinek, Ph.D. |
| Summary |
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Students, during the course, are introduced to the basic approaches, methods and algorithms from bioinformatics.
The lectures will provide the necessary amount of theory so that it can be applied during the individual work of the students on the tutorials.
Tutorials will provide space for discussing the problems, showing practical tasks and exercising on simple examples. |
| Learning Outcomes of the Course Unit |
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Graduate Course gives the following knowledge and skills:
basic theoretical background for Bioinformatics,
implementation and application of selected methods for DNA, RNA, proteins analysis.
practical application to real data.
Data visualization.
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| Course Contents |
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Introduction to Molecular Biology
Sequence Similarity
Suffix Tree
Database search
Alignment
Algorithm Needleman-Wunsch
Phylogeny Reconstruction
Phylogeny Comparison
RNA secondary structure prediction
DNA Sequencing
Population genetics |
| Recommended or Required Reading |
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| Required Reading: |
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Wing-Kin Sung. Algorithms in Bioinformatics: A Practical Introduction. Chapman & Hall/CRC Mathematical & Computational Biology. 2009.
Arthur Lesk. Introduction to Bioinformatics. Oxford University Press, 2014.
Pierre Baldi;G. Wesley Hatfield. DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling. Cambridge University Press 2002. |
Wing-Kin Sung. Algorithms in Bioinformatics: A Practical Introduction. Chapman & Hall/CRC Mathematical & Computational Biology. 2009
Arthur Lesk. Introduction to Bioinformatics. Oxford University Press, 2014.
Fatima Cvrčková. Úvod do praktické bioinformatiky. 1. vyd. Praha: Academia, 2006.
Pierre Baldi;G. Wesley Hatfield. DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling. Cambridge University Press 2002.
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| Recommended Reading: |
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| Caroline St. Clair, Jonathan E. Visick. Exploring Bioinformatics: A Project-Based Approach. Jones & Bartlett Learning, 2013. |
Caroline St. Clair, Jonathan E. Visick. Exploring Bioinformatics: A Project-Based Approach. Jones & Bartlett Learning, 2013.
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| Planned learning activities and teaching methods |
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| Lectures, Tutorials |
| Assesment methods and criteria |
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| Task Title | Task Type | Maximum Number of Points
(Act. for Subtasks) | Minimum Number of Points for Task Passing |
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| Graded credit | Graded credit | 100 | 51 |