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Organic and macromolecular chemistry

* Exchange students do not have to consider this information when selecting suitable courses for an exchange stay.

Course Unit Code9360-0120/03
Number of ECTS Credits Allocated5 ECTS credits
Type of Course Unit *Compulsory
Level of Course Unit *First Cycle
Year of Study *First Year
Semester when the Course Unit is deliveredSummer Semester
Mode of DeliveryFace-to-face
Language of InstructionCzech
Prerequisites and Co-Requisites Course succeeds to compulsory courses of previous semester
Name of Lecturer(s)Personal IDName
PLA88prof. Ing. Daniela Plachá, Ph.D.
Summary
Students will study fundamental principles of organic and macromolecular chemistry, that form an important base for studying of organic and polymeric nanostructures in next classes.
Learning Outcomes of the Course Unit
The aim of the course is to acquire basic knowledge in the field of organic and macromolecular chemistry, with an emphasis on the basic reaction mechanisms of organic compounds and an overview of the properties of organic substances, supplemented by an overview of technically important representatives.
Course Contents
1. Introduction to the study of organic compounds, structure and bonds in organic matter, nomenclature of organic compounds.
2. Stereochemistry, hybridization and structure of molecules, stereoisomers.
3. Hydrocarbons - alkanes and cycloalkanes, alkenes and cycloalkenes, alkynes, dienes, occurrence, structure, physical properties, typical reactions - radical substitution, electrophilic and radical addition, oxidation, a list of technically significant representatives.
4. Aromatic hydrocarbons, aromaticity, occurrence, structure, physical properties, electrophilic substitution, velocity and orientation in electrophilic aromatic substitution, oxidation-reduction reaction, a list of technically significant representatives.
5. Derivatives of hydrocarbons, overview of derivatives and their properties, halogen derivatives, occurrence, structure, physical properties, nucleophilic substitutions, nucleophiles, elimination reactions, a list of technically significant representatives.
6. Organometallic compounds, carbon-metal bond, preparation and reaction of organometallic compounds, a list of technically significant representatives.
7. Hydroxy derivatives, thiols, ethers, sulfides, occurrence, structure, physical properties, alcohol reactions, nucleophilic substitution, dehydration, esterification, oxidation of alcohols, a list of technically significant representatives.
8. Carbonyl compounds, occurrence, structure, physical properties, nucleophilic additions, rearrangements, electrophilic substitutions, aldolization, oxidation and reduction, a list of technically significant representatives.
9. Carboxylic compounds and functional derivatives of carboxylic acids, occurrence, structure, physical properties, reaction of carboxylic acids, reactivity of functional derivatives, a list of technically significant representatives.
10. Nitrogen compounds, occurrence, structure, physical properties, basicity and acidity of amines, acidity of nitrocompounds, reactions, a list of technically significant representatives.
11. Introduction to macromolecular chemistry, basic concepts, characteristics of macromolecular substances, structure and properties of polymers. polymer nomenclature, molecular weight of polymers, influence of molecular weights on properties of polymers, constituents of polymers, physical states of polymers.
12. Synthesis of polymers - types of polymerization, polymerization mechanisms, monomers, initiation and catalysis, propagation, conditions of propagation, copolymerization, terminations, inhibitors.
13. Overview of synthetic polymeric materials - distribution, structure, properties, application of polymer materials, polymer aging and processing, changes in chemical structure and their influence on physico-mechanical properties.
14. Structure and properties of natural polymers - proteins, polysaccharides, nucleic acids.
Recommended or Required Reading
Required Reading:
CLAYDEN, J., GREEVES, N., WARREN, S.: WOTHERS, P. Organic Chemistry. New York, Oxford University Press, 2001. 1512 p. ISBN 0-19-850346-6.
McMURRY J. Organic Chemistry. Volume 1-2, 2008, 2010.
McMURRY J. Fundamentals of Organic Chemistry. Brooke Cole. 2011.
Ravve A. Principles of Polymer Chemistry. Springer. 2012. 801 p. ISBN 978-1-4614-2211-2.
MARK, J.E. Physical Properties of Polymers Handbook.2007. 1076 p. ISBN 978-0-387-31235-4.
SVOBODA, J.: Organická chemie I. Praha, VŠCHT, 2005. 291 p. ISBN 80-7080-561-7.
McMURRY J.: Organická chemie. Praha, VŠCHT, 2007. 1270 p. ISBN: 978-80-7080-637.
PROKOPOVÁ, I.: Makromolekulární chemie. Praha, VŠCHT, 2005. 207 p. ISBN 80-7080-554-4.
McMURRY J. Organic Chemistry. Volume 1-2, 2008, 2010.
Recommended Reading:
CLAYDEN, J., GREEVES, N., WARREN, S., WOTHERS, P. Organic Chemistry. New York, Oxford University Press, 2001. 1512 p. ISBN 0-19-850346-6.
BRAUN, D., CHERDRON, H., REHAHN, M., RITTER, H., VOIT, B. Polymer Synthesis: Theory and Practice. Springer.2013. 402 p. ISBN 978-3-642-28979-8.
ČERVINKA, O., DĚDEK, V., FERLES, M.: Organická chemie. SNTL, Praha, 1980.
CLAYDEN, J., GREEVES, N., WARREN, S.: WOTHERS, P. Organic Chemistry. New York, Oxford University Press, 2001. 1512 p. ISBN 0-19-850346-6.
KUČERA, M.: Makromolekulární chemie. Synthesa molekul. Brno, VUTIUM, 1999. 157 p. ISBN 80-214-1330-1.
DUCHÁČEK, V.: Základní pojmy z chemie a technologie polymerů, jejich mezinárodní zkratky a obchodní názvy. Praha, VŠCHT, 1999 (2004 dotisk). ISBN 80-7080-265-0.
VODRÁŽKA, Z.: Biochemie. Praha, Scientia, s r.o., 1998. 161 p. ISBN 80-7183-083-6.
Planned learning activities and teaching methods
Lectures, Tutorials
Assesment methods and criteria
Task TitleTask TypeMaximum Number of Points
(Act. for Subtasks)
Minimum Number of Points for Task Passing
Credit and ExaminationCredit and Examination100 (100)51
        CreditCredit40 20
        ExaminationExamination60 35