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Biological nanostructures

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Course Unit Code9360-0148/04
Number of ECTS Credits Allocated3 ECTS credits
Type of Course Unit *Choice-compulsory type B
Level of Course Unit *Second Cycle
Year of Study *Second Year
Semester when the Course Unit is deliveredWinter Semester
Mode of DeliveryFace-to-face
Language of InstructionCzech
Prerequisites and Co-Requisites Course succeeds to compulsory courses of previous semester
Name of Lecturer(s)Personal IDName
LES05Prof. Mgr. Jana Kukutschová, Ph.D.
Summary
Students will achieve knowledge on biological nanostructures, their characteristics, biological functions, methods of synthesis and potential applications. The subject will deal with nanostructures based on proteins and nucleic acids and their potential use in nanotoechnologie, for example as thin layers, bio-sensors etc.
Learning Outcomes of the Course Unit
Students will be able to define biological nanostructures based on proteins, saccharides, lipids and nucleic acids and their properties and functions in living systems. Based on the knowledge obtained they will be able to characterize bionanomaterials and summarize their applications for instance in form of thin films and in devices such as biosensors, etc.
Course Contents
1. Definition of the field, first theories.
2. Cell structure, chemical composition of cells.
3. Chemical composition of human body.
4. Saccharides - structure, function in living systems.
5. Lipids - structure and function in living systems.
6. Aminoacids and peptides - structure and function in living systems.
7. Proteins - structure and function in living systems.
8. Nucleic acids - structure and function in living systems.
9. Mutagenesis, mechanisms of origination and effects on living systems.
10. Separation of natural biomolecules and examples of applications.
11. Synthesis of biomolecules and examples of applications.
12. Biological nanodevices, bacis elements, applications.
13. Biosensors - classification, examples of applications.
14. Monolayers, examples of thin multilayer films in biology.
Recommended or Required Reading
Required Reading:
Chen W., McCarthy T.: Macromolecules 30, 1997.
Nalwa H.S.: Handbook of Nanostructured Materials and Nanotechnology. Academic Press, 2000.
Benoit J.P., Marchais H., Velde V.V.: Microencapsulation Methods and Industrial Applications (S. Benita, ed.). Marcel Dekker, New York, 1996.
Chen W., McCarthy T.: Macromolecules 30, 1997.
Nalwa H.S.: Handbook of Nanostructured Materials and Nanotechnology. Academic Press, 2000.
Benoit J.P., Marchais H., Velde V.V.: Microencapsulation Methods and Industrial Applications (S. Benita, ed.). Marcel Dekker, New York, 1996.
Recommended Reading:
Chandran K., Kalpana B., Robson B.: Biosensors and Bioelectronics. Elsevier, 2015, ISBN: 9780128031001
Higson S.: Biosensors for Medical Applications. Springer, Woodhead Publishing Limited, 2012, ISBN: 978-1-84569-935-2
Chandran K., Kalpana B., Robson B.: Biosensors and Bioelectronics. Elsevier, 2015, ISBN: 9780128031001.
Higson S.: Biosensors for Medical Applications. Springer, Woodhead Publishing Limited, 2012, ISBN: 978-1-84569-935-2.
Planned learning activities and teaching methods
Lectures
Assesment methods and criteria
Task TitleTask TypeMaximum Number of Points
(Act. for Subtasks)
Minimum Number of Points for Task Passing
ExaminationExamination100 51