| Course Unit Code | 9360-0196/01 |
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| Number of ECTS Credits Allocated | 2 ECTS credits |
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| Type of Course Unit * | Compulsory |
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| Level of Course Unit * | Second Cycle |
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| Year of Study * | Second Year |
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| Semester when the Course Unit is delivered | Summer Semester |
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| Mode of Delivery | Face-to-face |
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| Language of Instruction | Czech |
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| Prerequisites and Co-Requisites | Course succeeds to compulsory courses of previous semester |
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| Name of Lecturer(s) | Personal ID | Name |
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| LES05 | Prof. Mgr. Jana Kukutschová, Ph.D. |
| MOT127 | Mgr. Oldřich Motyka, Ph.D. |
| Summary |
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| The subject is focused on various apsects of release, transformation and potential impact of occurence of nanomaterials in single environmental compartments. Key parameters of nanomaterials having decisive impact on potential adverse effects related to occurence of nanomaterials in the environment also with respect to exposure of living organisms to these materials are emphasized. Moreover, nanomaterials as contaminants of single environmental compartments (i.e. air, water and soil) and resulting potential adverse effects are discussed together with the issue of the end phase of nanomaterials life-cycle when there are becoming wastes. Due to the exposure of living systems to nanomaterials present in the environment also the topic of nanomaterials efects on molecular, celullar and organ levels for organisms from single trophic levels is discussed. The topic of ethical aspects and legislative framework are also included with respect to the nanomaterials assessment and applications. |
| Learning Outcomes of the Course Unit |
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| Student who successfully complete the subject is able to define key parameters of nanomaterials which contribute to their environmental risks. Further, the student can explain potential transport routes of nanomaterials in the environment, their potential (bio)transformation and (bio)accumulation within the environmental fate. The student is able to discuss single aspects of air, water and soil contamination issues and evaluate risks of nanomaterials in form of wastes and moreover to describe potential adverse effects of nanomaterials to living organisms on molecular, cellular and organ levels. With respect to applications of nanomaterials and their impact he/she is able to outline potential ethical issues of these applications and pre-application assessment of nanomaterials and also to describe legislative framework of this issue. |
| Course Contents |
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1. Toxicologically significant parameters of nanomaterials (NMs)
2. Environmental fate, transport of NMs in the environment
3. Biotransformation of selected NMs
4. Bioaccmulation, deposition in single parts of an organism
5. Contamination of air
6. Contamination of water
7. Contamination of soil
8. NMs as wastes
9. In vitro and in vivo methods for toxicity assessment of NMs
10. Effects of NMs on molecular and cellular level
11. Ecotoxicity of NMs
12. Genotoxic effects of selected NMs
13. Ethical aspects of NMs usage
14. Regulatory framework of NMs usage |
| Recommended or Required Reading |
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| Required Reading: |
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Houdy P.: Nanoethics and Nanotoxicology. Springer, 2011, ISBN: 978-3-642-20176-9.
Theodore L., Kunz R.G.: Nanotechnology: Environmental Implications and Solutions. Wiley & Sons, 2005, ISBN: 978-0-471-69976-7. |
Houdy P.: Nanoethics and Nanotoxicology. Springer, 2011, ISBN: 978-3-642-20176-9.
Theodore L., Kunz R.G.: Nanotechnology: Environmental Implications and Solutions. Wiley & Sons, 2005, ISBN: 978-0-471-69976-7. |
| Recommended Reading: |
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Vogel U., Savolainen K., Wu Q., van Tongeren M., Brouwer D., Berges M.: Handbook of Nanosafety, Measurement, Exposure and Toxicology, Elsevier 2014, ISBN: 9780124166042.
Dhawan A.: Nanotoxicology: Experimental and Computational Perspectives, Royal Society of Chemistry 2018, ISBN: 978-1-78262-158-4. |
Vogel U., Savolainen K., Wu Q., van Tongeren M., Brouwer D., Berges M.: Handbook of Nanosafety, Measurement, Exposure and Toxicology, Elsevier 2014, ISBN: 9780124166042
Dhawan A.: Nanotoxicology: Experimental and Computational Perspectives, Royal Society of Chemistry 2018, ISBN: 978-1-78262-158-4 |
| Planned learning activities and teaching methods |
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| Lectures |
| Assesment methods and criteria |
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| Task Title | Task Type | Maximum Number of Points
(Act. for Subtasks) | Minimum Number of Points for Task Passing |
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| Examination | Examination | 100 | 51 |