Skip to main content
Skip header

Biocompatible Materials

* Exchange students do not have to consider this information when selecting suitable courses for an exchange stay.

Course Unit Code637-3007/04
Number of ECTS Credits Allocated5 ECTS credits
Type of Course Unit *Compulsory
Level of Course Unit *Second Cycle
Year of Study *First Year
Semester when the Course Unit is deliveredWinter Semester
Mode of DeliveryFace-to-face
Language of InstructionCzech
Prerequisites and Co-Requisites There are no prerequisites or co-requisites for this course unit
Name of Lecturer(s)Personal IDName
LOS35doc. Dr. Ing. Monika Losertová
Summary
Subject deals with materials used in orthodontics, orthopedics, traumatology, cardiovascular surgery, neurosurgery and neurology, with basic features of biocompatibility and bioactivity and with the history of applications. Materials are classified as metallic, ceramic, polymer and composite. Basic features, mechanical and corrosion properties, surface treatment, anticorrosion protection, stress shielding problems on implant/living tissue will be discussed. Biodegradation and bioresorption will be treated in relation of recent findings.
Learning Outcomes of the Course Unit
Student should be able to do the following:
- classify and explain various type of materials
- define and explain basic parameters of various material groups
- analyse and evaluate possible applications of the acquired findings for preparation of new materials
- formulate advantages and disadvantages of various materials
- optimize material and technological parameters of materials from the viewpoint of applications in vivo
- define possible interactions with surrounding environment in vitro and in vivo
- apply the findings at solution of problems in the given domain
Course Contents
1. Introductory, overview of materials applied in biomedicine, basic characteristics of biocompatibility, history of applications.
2. Materials used in orthodoncy, orthopedics, traumatology, cardiovasculary surgery, neurosurgery and neurology.
3.-5. Biocompatible metallic materials, aplications, categories of materials, mechanical, corrosive properties, surface treatment, anticorrosion protection.
6. Challenge of strains on the implants/living tissue interface
7. Ceramic materials and coatings used in implants
8. Materials on the base of natural or synthetic polymers, characteristics, overview of materials. Gels.
9. Composite material, mechanical and corrosive properties, surface treatment.
10. Biodegradability and bioresorbence (in relation with new knowledges)
11. New applications of nanostructured materials and materials inspired by living nature.
12. Application of active medicinal substances on the implant surfaces.
Recommended or Required Reading
Required Reading:
1. HIN, T. S. Biomaterials Engineering and Processing. Series-Vol.1 - Engineering Materials for Biomedical Applications. 2004. ISBN 981-256-061-0
2. RATNER, B.D., A.S. HOFFMAN, F.J.SCHOEN a J.E. LEMONS ed. Biomaterials Science. An Introduction to Materials in Medicine. Third Edition. Elsevier Inc. 2013. ISBN 978-0-12-374626-9
3. NIINOMI, M., et al. Development of new metallic alloys for biomedical applications. Acta Biomaterialia, 8, 2012, 3888-3903
4. GEETHA, M., et al. Ti based biomaterials, the ultimate choice for orthopaedic implants – A review. Progress in Materials Science 54, 2009, 397-425.
1. LOSERTOVÁ, M. Biokompatibilní materiály. Studijní opora k předmětu, 2013.
2. HIN, T. S. Biomaterials Engineering and Processing. Series-Vol.1 - Engineering Materials for Biomedical Applications. 2004. ISBN 981-256-061-0
3. RATNER, B.D., A.S. HOFFMAN, F.J.SCHOEN a J.E. LEMONS ed. Biomaterials Science. An Introduction to Materials in Medicine. Third Edition. Elsevier Inc. 2013. ISBN 978-0-12-374626-9
Recommended Reading:
1. DONACHIE, M.J. Titanium. A Technical Guide. ASM International Park, Ohio 2000, ISBN 0-87170-309-2
2. BOYER, R., et al. Materials Properties Handbook: Titanium Alloys, ASM, Materials Park, USA, 1994, s. 94–111.
1. LOSERTOVÁ, M. Progresivní materiály. Studijní opora, 2012. ISBN 978-80-248-2575-5
2. NIINOMI, M., et al. Development of new metallic alloys for biomedical applications. Acta Biomaterialia, 8, 2012, 3888-3903.
Planned learning activities and teaching methods
Lectures, Individual consultations, Tutorials, Experimental work in labs, Project work
Assesment methods and criteria
Task TitleTask TypeMaximum Number of Points
(Act. for Subtasks)
Minimum Number of Points for Task Passing
Credit and ExaminationCredit and Examination100 (100)51
        CreditCredit45 25
        ExaminationExamination55 15