1. Current data of toxicology conception, case - history, toxicology classification , characteristic of branch. Toxicology concept in wider context of natural sciences, determination of basic conceptions, case history.
2. Definition of terms. Toxic matter and toxicity. Toxic effects (characteristic, formulation). Poisons classification and their incidence on organism. Exposition.
3. Dose (relation dose and effect). Interaction between toxic matters. Factors of influencing toxic effect.
4. Management techniques of determination toxicity matters, bio-transformation conversion. Bio-transformation (axioms, phase, factors influencing bio - transformation).
5. Toxocinetics - interaction of toxic matters with organism (primary contact, absorption, distribution and transport toxic matters in organism, elimination).
6. Toxicology at molecules and cell level. Mechanism of penetration toxic matters over bio-membrane. Effects of noxas on organ level (mechanism, symptom effect, example of matters).
7. Mutagenesis, carcinogenese, reproductive and evolutional toxicity. Method assesment levels of exposition, exposition limits.
8. Significant inorganic harmful substances and their effects on organism.
9. Significant organic harmful matters and their effects.
10. Safety factor of work in chemistry, law regulations, source of information.
11. Principals of first help at accident and poisonings in laboratory
12. – 13. Ecotoxicology.
14. Present - day problems in environmentu.
2. Definition of terms. Toxic matter and toxicity. Toxic effects (characteristic, formulation). Poisons classification and their incidence on organism. Exposition.
3. Dose (relation dose and effect). Interaction between toxic matters. Factors of influencing toxic effect.
4. Management techniques of determination toxicity matters, bio-transformation conversion. Bio-transformation (axioms, phase, factors influencing bio - transformation).
5. Toxocinetics - interaction of toxic matters with organism (primary contact, absorption, distribution and transport toxic matters in organism, elimination).
6. Toxicology at molecules and cell level. Mechanism of penetration toxic matters over bio-membrane. Effects of noxas on organ level (mechanism, symptom effect, example of matters).
7. Mutagenesis, carcinogenese, reproductive and evolutional toxicity. Method assesment levels of exposition, exposition limits.
8. Significant inorganic harmful substances and their effects on organism.
9. Significant organic harmful matters and their effects.
10. Safety factor of work in chemistry, law regulations, source of information.
11. Principals of first help at accident and poisonings in laboratory
12. – 13. Ecotoxicology.
14. Present - day problems in environmentu.