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Terminated in academic year 2021/2022

Organic Chemistry and Biochemistry

Type of study Bachelor
Language of instruction Czech
Code 617-0016/05
Abbreviation OCHBCH
Course title Organic Chemistry and Biochemistry
Credits 5
Coordinating department Department of Chemistry
Course coordinator doc. Ing. Lenka Kulhánková, Ph.D.

Subject syllabus

1. Lecture:
Introduction into the organic chemistry. History of organic chemistry. Bonding properties of carbon. Intermolecular interaction. Principles of stereochemistry of organic compounds. Drawing organic molecules. Polymerism and isomerism.
Seminary:
Bonding properties of carbon. Inference of molecular, rational and structural formula. Determination of isomerism type in the specific compounds.

2. Lecture:
Chemical reactions of organic compounds. Ranking of organic reactions. Homolysis and heterolysis. Electrophilic and nucleophilic agents. Aliphatic, alicyclic, saturated and unsaturated hydrocarbons. Nomenclature of hydrocarbons. Physical properties, important reactions and application.
Seminary:
Nomenclature of organic compounds.

3. Lecture:
Aromatic compounds. Delocalization of  electrons. Physical properties, toxicity, application and important reactions. Derivatives of hydrocarbons. Derivatives of halogens. Physical properties, toxicity, application and important reactions.
Seminary:
Nomenclature of organic compounds.

4. Lecture:
Derivatives of sulfure (thioalcohols and thiophenols, sulphides, sulfonic acids). Physical properties, application and important reactions. Derivatives of nitrogen (nitrocompounds, amines, diazonium salts, azocompounds). Physical properties, toxicity, application and important reactions.
Seminary:
Nomenclature of organic compounds.

5. Lecture:
Derivatives of oxygen (alcohols, phenols, ethers). Physical properties, toxicity, application and important reactions. Carbonyl compounds (aldehydes and ketones). Physical properties, toxicity, application and important reactions.
Seminary:
Nomenclature of organic compounds.

6. Lecture:
Carboxylic acids. Physical properties, application and important reactions.
Seminary:
Nomenclature of organic compounds

7. Lecture:
Derivatives of carboxylic acids. Physical properties, application and important reactions.
Experimental work in lab:
Preparing of fumaric acid.

8. Lecture:
Introduction into the biochemistry. Characterization of living organisms.
Experimental work in lab:
Preparing of jodoform.

9. Lecture:
Amino-acids (structure and properties). Peptides (structure and properties). Proteins (structure and properties).
Experimental work in lab:
Preparing of acetylsalicyclic acid.

10. Lecture:
Saccharides (monosaccharides, glycosides, oligosaccharides and polysaccharides).
Experimental work in lab:
Saccharides.

11. Lecture:
Lipids (characterization and structuring lipids). Terpenes. Steroids.
Experimental work in lab:
Extraction of essential oils.


12. Lecture:
Biotechnology. Detergents.
Experimental work in lab:
Separation of leaf days.

13. Lecture:
Alkaloids (properties and structuring alkaloids).
Experimental work in lab:
Alkaloids and tanstuffs.

14. Lecture:
Enzymes (classification, constitution and molecular properties of enzymes).
Seminary:
Presentation of seminar papers.




Literature

1) McMurry, J. Organic chemistry - 6th ed. - Belmont: Thomson Brooks/Cole, 2004, ISBN 0-534-38999-6.
2) Karlson, P. Biochemistry. 4th edition -Academic Press New York, 1975, ISBN 0123997313 

Advised literature

Recommended English literature will be selected on the basis of individual consultations.