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Terminated in academic year 2016/2017

Organic and Macromolecular Chemistry

Type of study Bachelor
Language of instruction Czech
Code 617-0404/01
Abbreviation OMCH
Course title Organic and Macromolecular Chemistry
Credits 7
Coordinating department Department of Chemistry
Course coordinator doc. Ing. Petr Pánek, CSc.

Subject syllabus

1.Theoretical basis of organic chemistry, bonding properties of carbon, structure theory, theory of chemical bonds. Types of bonds, inductive and mesomeric effects; types of formulas, models and 3D presentations. Nomenclature of Organic Chemistry.

2.The structure of organic compounds, the shape of molecules, types of isomerism, conformery, absolute and relative configuration. Interactions between molecules and physicochemical properties of organic compounds.

3.Organic reactions. Thermodynamics, kinetics and mechanisms of organic reactions. Cleavage of bonds, types of agents. Bröndsted and Lewis theories of acids and bases, the relationship between structure and acidity, respectively basicity.Oxidation and reduction reactions in organic chemistry.

4.Alkanes and cycloalkanes, their physical and physiological characteristics, methods of
acquisition, chemical properties and reactivity, substitution reaction of radicals (SR), cracking. Alkenes and polyenes, methods of obtaining, isomerism, chemical properties, electrophilic and radical adition (AE, AR), hydrogenation, polymerization, allylic substitution. Alkynes, their physical properties, methods of synthesis and reactivity.

5.Arenes. Aromatic state. Aromatic hydrocarbons, their reactivity, electrophilic aromatic substitution (SEAR), nucleophilic aromatic substitution (SNARE). Polyaromatic and their toxicity.

6. Halogen derivatives of aliphatic and aromatic hydrocarbons, methods of synthesis, properties and reactivity, nucleophilic substitution (SN1, SN2), elimination reactions (E1, E2). Organometallic compounds, preparation and utilization.

7. Alcohols and phenols, ethers and their sulfur analogues , methods of synthesis,
reactivity, utilization.

8. Nitrogen derivatives - amines, azo compounds, diazo compounds, nitro and nitroso compounds and oximes, their properties and reactivity.

9.Carbonyl compounds - aldehydes and ketones, their properties and reactivity, nucleophilic addition to a polarized multiple bond, the reaction of enolat ionts. Dicarbonyl and unsaturated carbonyl compounds.

10.Carboxylic acids and their functional and substitution function derivatives, properties and reactivity.

11,Basic heterocyclic compounds and their reactivity. Five-and six-membered heterocycles derived from oxygen, nitrogen and sulfur. Terminology.

12. Basic chemistry of macromolecular compounds, polymer types and structure, utilization of the technological most important groups of polymers.

13.Methods of the studying organic compounds. Sources of the industrial organic chemistry. Petrochemistry and chemistry of coal tar and pitch. The importance of organic chemistry for the modern human society.

Laboratory:
1. Laboratory syfety guidelines. Basic laboratory techniques.
2. Product identification (boiling and melting point, index of refraction, TLC, IR spectroscopy)
3.-12. Important classis of reactions.

Literature

[1] W. H. Brown: Organic Chemistry (Saunders College Publishing, 1995)
[2] W. H. Brown: Organic Polymer Chemistry: (Saunders College Publishing, 1995)

Advised literature

[1] Solomons, T. W. G., Fryhle, C. B.: Organic Chemistry (John Wiley & Sons, New York, Chichester, Weinheim 2000)