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Organic Chemistry

Type of study Bachelor
Language of instruction English
Code 651-2019/03
Abbreviation OCh
Course title Organic Chemistry
Credits 5
Coordinating department Department of Chemistry and Physico-Chemical Processes
Course coordinator doc. Ing. Lenka Kulhánková, Ph.D.

Subject syllabus

Lectures
1. Introduction into the organic chemistry. Bonding power of carbon. Relation between the structure and the properties of substances. Intermolecular interaction and their influence on the melting temperature, boiling temperature and solubility.
2. Principles of stereochemistry of organic compounds. Drawing organic molecules. Polymerism and isomerism. The conformation of organic compounds.
3. Chemical reactions of organic compounds. Classification of organic reactions. Aliphatic and alicyclic hydrocarbons. The physical and chemical properties of aliphatic and alicyclic hydrocarbons. Resources of hydrocarbons and their application.
4. Unsaturated hydrocarbons. The physical and chemical properties of unsaturated hydrocarbons. Resources of unsaturated hydrocarbons and their industrial application.
5. Aromatic hydrocarbons. The physical and chemical properties of aromatic hydrocarbons. Resources of aromates and their industrial application. Toxicity of polyaromatic compounds.
6. Halogen derivatives. Reactivity, properties and toxikology. Application of halogen derivatives.
7. Nitrogen derivatives of hydrocarbons. Reactivity, properties and toxikology. Synthesis and important reactions. Alkaloids.
8. Sulfur derivatives of hydrocarbons. Physical properties. Synthesis and important reactions. Detergents.
9. Oxygen derivatives of hydrocarbons. Hydroxyderivatives. Ethers. Physical properties, toxikology and their application.
10. Carbonyl compounds. The physical and chemical properties. The application of carbonyl compounds. Organometallic compounds. Reactivity, toxikology and their application. Grignard reagents and their reactions.
11. Carboxylic acids. Physical properties. Preparation, importance and application of carboxylic acids.
12. Substitutional derivatives of carboxylic acids. Reactivity, properties and their application.
13. Functional derivatives of carboxylic acids. Reactivity, properties toxikology and their application.
14. Polymers (types, basic reactions of polymers preparation, overview of technically most important polymers).


Theoretical tutorials
- Introductory information (schedule of the seminar, the conditions for obtaining credit and recommended literature). Bonding power of carbon. Structure, formula, model. Inference of molecular formula, rational formula and structural formula. Determination of isomerism type for given compounds.
- Nomenclature of organic compounds.
- Nomenclature of organic compounds.
- Nomenclature of organic compounds.
- Nomenclature of organic compounds.
- Nomenclature of organic compounds.


Experimental work in labs
- Preparation of fumaric acid.
- Preparation of iodoform.
- Preparation of acetylsalicylic acid.
- Preparation of acetanilide.
- Preparation of 4-nitroaniline.
- Preparation of para red.
- Preparation of fumaric acid.
- Preparation of acetylsalicylic acid.

Literature

MCMURRY, John. Organic chemistry. 6th ed. Belmont: Thomson Brooks/Cole, c2004. ISBN 0-534-38999-6.

Advised literature

SOLOMONS, T. W. Graham a Craig B. FRYHLE. Organic chemistry [CD-ROM]. 8th ed. Hoboken: Wiley, c2004. ISBN 0-471-41799-8.