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Basics of biochemistry and cell biology

Type of study Bachelor
Language of instruction Czech
Code 9360-0304/01
Abbreviation ZBBB
Course title Basics of biochemistry and cell biology
Credits 6
Coordinating department CNT - Nanotechnology Centre
Course coordinator Ing. Sylva Holešová, Ph.D.

Subject syllabus

1. Introduction to biochemistry. Importance of biochemistry. Chemical composition of living organisms. Organization of living systems. Metabolism. Examples of the use of biochemical processes.
2. Amino acids and peptides. Structure and nomenclature. Acid-base properties of amino acids. Chemical reactions of amino acids. Peptides. Hormones.
3. Proteins. Classification of proteins. Chemical and spatial structure. Non-covalent interactions. Properties and functions of proteins. Enzymes.
4. Lipids. Chemical structure and function of lipids. Composition of the biological membrane. Transport across membranes.
5. Nucleic acids. Structure of nucleic acids. Nucleosides, nucleotides. Structure of DNA, RNA. Molecular genetics.
6. Carbohydrates and polysaccharides. Classification, structure. Derivatives of carbohydrates.
7. Prokaryotic and eukaryotic cells, differences, adaptation, and evolution. Bacteria, Archaea, and Eukaryota.
8. Metabolism and energy transformation in organisms. Anabolism, catabolism. Transformations of substances.
9. Animal cell – structure, organelles, function.
10. Plant cell – structure, organelles, function.
11. Physiology of animal cells.
12. Physiology of plant cells.
13. Cell cycle, cell division, mitosis, meiosis.
14. Cell stress factors, apoptosis, necrosis.

Literature

1. KODÍČEK, Milan, Olga VALENTOVÁ a Radovan HYNEK. Biochemie. Chemický pohled na biologický svět. 2. vyd. Praha: VŠCHT, 2018. ISBN 978-80-7592-013-3 .
2. KODÍČEK, Milan, 2004. Biochemické pojmy: výkladový slovník. Praha: Vysoká škola chemicko-technologická. ISBN 978-80-7080-551-0 .
3. ALBERTS, Bruce, [2006]. Základy buněčné biologie: úvod do molekulární biologie buňky. 2. vyd. Ústí nad Labem: Espero. ISBN 80-902-9062-0.
4. NEČAS, Oldřich. Obecná biologie pro lékařské fakulty. Jinočany, 2000. ISBN 80-860-2246-3 .

Advised literature

1. MURRAY, Robert a kol. Harperova ilustrovaná biochemie. Galén, 2012. ISBN 978-80-7262-907-7 .
2. MCMURRY, John. Organická chemie. Přeložil Jaroslav JONAS. V Brně: VUTIUM; V Praze, 2007. ISBN 978-80-214-3291-8.
3. NOVÁČEK, František. Fytochemické základy botaniky. Vyd. 2., dopl. Olomouc: Fontána, 2008. ISBN 978-80-7336-457-1 .
4. ZÁVODSKÁ, Radka, Denis BRAY a Alexander JOHNSON. Biologie buněk: základy cytologie, bakteriologie, virologie. 2. vyd. Praha: Scientia. Biologie pro gymnázia, 20006. ISBN 80-869-6015-3.