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Industrial (occupational) toxicology

Type of study Bachelor
Language of instruction Czech
Code 040-0611/01
Abbreviation PTX
Course title Industrial (occupational) toxicology
Credits 3
Coordinating department Department of Occupational and Process Safety
Course coordinator Ing. Petra Roupcová, Ph.D.

Subject syllabus

1. Definition of the subject toxicology, classification of poisons, relationship between the structure of the substance and its toxicity, toxicity evaluation, factors affecting the toxic effect, entry of substances into the body, distribution and mechanisms of action of poisons,
2. Interaction of toxins with the cell, biotransformation and its phases, exposure, toxic substances in the environment and work environment, ecotoxicology,
3. Effects of poisons on organism and organ toxicity - hematotoxic, hepatotoxic, immunotoxic and neurotoxic substances, mutagenic and carcinogenic substances, addictive substances,
4. toxicity of combustion products,
5. Toxicity of raw materials, intermediates, products and wastes of selected chemical productions (inorganic and organic production),
6. Toxicity of industrial gases (chlorine, ammonia, hydrogen),
7. Petrochemistry, toxicity of oil processing product,
8. Chemistry of phosphorus, phosphates and organophosphates of nerve agent,
9. Division of pesticides according to the efficiency of the segment, focus on ecotoxicity,
10. Organic solvents, examples, their risks in application including toxicity,
11. Metals and metal compounds, influence of ionic form on toxicity,
12. Natural toxins with a focus on mycotoxins,
13. Toxicity of nanoparticles with a focus on nanoparticles specifically produced such as graphene, graphene oxide, fullerene, titanium and zinc oxides and the like

Literature

KUBÁTOVÁ Hana. Průmyslová toxikologie a životní prostředí. Ostrava: Sdružení požárního a bezpečnostního inženýrství, 2018, ISBN 978-80-7385-210-8

Advised literature

LINHART Igor. Toxikologie: Interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. 2. vydání, Praha: VŠCHT v Praze, 2014, ISBN 978-80-7080-877-1
HORÁK Josef, LINHART Igor, KLUSOŇ Petr. Úvod do toxikologie a ekologie pro chemiky. Praha: VŠCHT v Praze, 2004, ISBN 978-80-7080-548-0
GILBERT Steven G. A small dose of toxicology: The Health effect of Common Chemicals. 2nd issue, Seattle: Healthy World Press, 2012, ISBN 978-0-9833378-3-6