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Physiology and Pathophysiology for Engineering

Type of study Bachelor
Language of instruction Czech
Code 546-0122/01
Abbreviation ZFP
Course title Physiology and Pathophysiology for Engineering
Credits 4
Coordinating department Department of Environmental Engineering
Course coordinator doc. Mgr. Kristina Čabanová, Ph.D.

Subject syllabus

1) General causes of diseases, etiology and pathogenesis, syndrome/symptom. External factors causing diseases. physical, chemical and biological pathogenic factors.
2) Cell/tissue/organ, regulation of cell proliferation, differentiation and death (necrosis vs. apoptosis), tissue damage, inflammation, local and systemic manifestations, cytokines and chemokines, general manifestations of diseases (fever, pain), regeneration vs. reparation, wound healing and its disorders.
3) Fundamentals of genetics, genetic variability, diseases due to chromosome aberrations, monogenic vs. complex (civilization) diseases.
4) Control of the cell cycle, tumor transformation of the cell, carcinogens, metastasis, interaction between the tumor and the organism, sporadic vs. familial forms.
5) Pathophysiology of the respiratory system.
6) Pathophysiology of blood.
7) Pathophysiology of the circulatory system.
8) Pathophysiology of the excretory system.
9) Homeostasis. Disorders of homeostasis.
10) Pathophysiology of the digestive system.
11) Pathophysiology of internal secretion.
12) Metabolic disorders.
13) Pathophysiology of allergic and autoimmune diseases. Nutritional disorders.

Literature

COSTANZO, Linda S. Physiology, E-Book. Elsevier Health Sciences, 2009.
MCCANCE, Kathryn L.; HUETHER, Sue E. Pathophysiology-E-book: the biologic basis for disease in adults and children. Elsevier Health Sciences, 2018.
SOLOMON, Eldra Pearl. Introduction to human anatomy and physiology. Elsevier Health Sciences, 2015.

Advised literature

SILBERNAGL, S.; DESPOPOULOS, A. Color Atlas of Physiology. 6th. New York: Thieme, 2009.