1. Introduction to industrial and environmental toxicology; literature, information sources; definitions, dose-effect relationship, toxicity, substance interactions at different levels; toxicokinetics; bioavailability, etc.
2. Principles of toxicology related to industry and the environment; dose-response; toxicity mechanisms, hazard assessment principles. Hazardous physicochemical properties, their testing. Individual types of toxic effects and possibilities of influencing them.
3. Methods of classification of chemical substances in the Czech Republic and the EU. The current system of classification of substances hazardous to health and the environment and risk assessment system. Safety of chemical products, some internationally monitored groups of chemical substances. Current chemical legislation
4. Introduction to the toxicology of the main classes of industrial and environmental compounds. Testing and evaluation of ecotoxicity and other properties dangerous for the environment, substances and mixtures dangerous for the environment.
5. Origin and types of waste in industrial production. Chemical properties of waste from industrial production. Hazardous substances in waste, hygienic and toxicological aspects of the generation, use and disposal of waste, management of hazardous waste from industrial production.
6. Biocidal substances; insecticides, rodenticides, pesticides. Antibacterial agents. Antibiotics. Antifungals. Virostatics. Protozoal biocides. Cytostatics. Antiseptics. Effects on humans and the environment.
7. Drugs in the environment. Indirect exposure to the human population. Sources of emissions. Ecotoxicology of drugs.
8. Ecotoxically important environmental pollutants (oxides of sulfur, nitrogen, ozone, nitrates, cyanides, PAHs, PCBs, dioxins, other pollutants from industrial production) and their monitoring. Pollutant cycle in the environment.
9. Substances produced by industry and their occurrence in plants. Protective and preventive measures in industrial production. Determination of toxic properties from the literature: toxicological data (LD, LC, NOAEL, LOAEL, etc.), toxicological databases, safety data sheets.
10. Toxicological characteristics of organic compounds, organoelement and organometallic compounds - mechanism of interaction in the organism and the environment, transport and metabolism.
11. Toxicology of industrial raw materials, intermediate products, products and waste pollutants in selected organic technological processes. Toxicologically important organic substances (benzene, asbestos, glycols, vinyl chloride, products of the petrochemical industry, etc.) in the work environment: occurrence, side effects and prevention.
12. Toxicological characteristics of elements, hazardous metals, inorganic compounds in selected technological processes (production of acids, bases, salts, ammonia, fertilizers, etc.). Toxicologically important metals in the work environment: occurrence, side effects and prevention.
13. Pollution by toxic elements from mineral processing: occurrence, side effects and prevention.
2. Principles of toxicology related to industry and the environment; dose-response; toxicity mechanisms, hazard assessment principles. Hazardous physicochemical properties, their testing. Individual types of toxic effects and possibilities of influencing them.
3. Methods of classification of chemical substances in the Czech Republic and the EU. The current system of classification of substances hazardous to health and the environment and risk assessment system. Safety of chemical products, some internationally monitored groups of chemical substances. Current chemical legislation
4. Introduction to the toxicology of the main classes of industrial and environmental compounds. Testing and evaluation of ecotoxicity and other properties dangerous for the environment, substances and mixtures dangerous for the environment.
5. Origin and types of waste in industrial production. Chemical properties of waste from industrial production. Hazardous substances in waste, hygienic and toxicological aspects of the generation, use and disposal of waste, management of hazardous waste from industrial production.
6. Biocidal substances; insecticides, rodenticides, pesticides. Antibacterial agents. Antibiotics. Antifungals. Virostatics. Protozoal biocides. Cytostatics. Antiseptics. Effects on humans and the environment.
7. Drugs in the environment. Indirect exposure to the human population. Sources of emissions. Ecotoxicology of drugs.
8. Ecotoxically important environmental pollutants (oxides of sulfur, nitrogen, ozone, nitrates, cyanides, PAHs, PCBs, dioxins, other pollutants from industrial production) and their monitoring. Pollutant cycle in the environment.
9. Substances produced by industry and their occurrence in plants. Protective and preventive measures in industrial production. Determination of toxic properties from the literature: toxicological data (LD, LC, NOAEL, LOAEL, etc.), toxicological databases, safety data sheets.
10. Toxicological characteristics of organic compounds, organoelement and organometallic compounds - mechanism of interaction in the organism and the environment, transport and metabolism.
11. Toxicology of industrial raw materials, intermediate products, products and waste pollutants in selected organic technological processes. Toxicologically important organic substances (benzene, asbestos, glycols, vinyl chloride, products of the petrochemical industry, etc.) in the work environment: occurrence, side effects and prevention.
12. Toxicological characteristics of elements, hazardous metals, inorganic compounds in selected technological processes (production of acids, bases, salts, ammonia, fertilizers, etc.). Toxicologically important metals in the work environment: occurrence, side effects and prevention.
13. Pollution by toxic elements from mineral processing: occurrence, side effects and prevention.