The course "Basics of toxicology" introduces students to the harmful toxic effects of chemicals (inorganic and organic), including methods of entry of these substances into the human body and their more detailed metabolism (biotransformation), including procedures of degradation (excretion) of toxic substances (xenobiotics), description toxicodynamic and toxicokinetic concepts, explanation of other concepts such as efficiency, dose, distribution, the effect of time (acute, chronic effects), absorption, etc. Part of the course is devoted to effect in the human body, the effect of toxic substances on mutation, carcinogenicity, reproduction, mutagenicity, as well as the effect of the toxicity of harmful substances on the function of individual organs in the human body in which toxic substances are eliminated or intoxication is observed. Furthermore, the course acquaints students with applicable laws and associated regulations and decrees in the field of chemical substances and chemical preparations, determining of the classification of substances or mixtures according to CLP 1272/2008/EC, current GHS regulation, labelling and packaging of substances and mixtures, Law No. 61/2014 Coll., on chemical substances and chemical mixtures and on the change of certain laws (Chemical law). Another form is information on the use of knowledge of toxicology in the field of chemistry, or in other fields, i.e. keeping records of chemicals, job description and handling of these substances, providing 1. aid with poisoning, safety issues with chemicals and laboratory safety.