1. Introduction to toxicology (history), its structure and content. Explanation of credit requirements (completion of the course). Toxicology division. Poisons and other pollutants. Poisons in the history. Theory of toxicity.
2. Routes of entry of substances into the human body (absorption, biotransformation, distribution process). Overview of the effects of poisons in the body. Acute and chronic effects of poisons in the body. General principles of treatment of poisoning. Toxicology versus other technical fields.
3. Explanation of important basic concepts in toxicology. The mechanism of effect of toxic substances, factors influencing the effects of toxic substances (including membrane entry). Interaction of toxic substances in the body.
4. Metabolism and disposal of toxins in the human body, first aid for acute poisoning, the treatment of chronic poisoning. Preventive protection against exposure to toxic and harmful substances.
5. Teratogenicity, mutagenicity, carcinogenicity of toxic substances, explanation of the organism-xenobiotic relationship.
6. The influence of the environment on toxicity, external influences, determination of toxicity for unknown substances. Influence of nanosubstances on toxicity (perspectives-advantages and disadvantages).
7. Valid legislation relating to toxic and harmful to health substances. Legislation Law: Corrigendum to Regulation (EC) No. 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures, regulation GHS, Law No. 61/2014 Coll.
8. Classification and coding of toxicological properties and hazards of chemical substances and preparations. (H, P sentences, signal words, etc.).
9. Toxicity of selected elements and inorganic compounds, part 1.
10. Toxicity of selected elements and inorganic compounds, part 2.
11. Toxicity of selected elements and inorganic compounds, part 3.
12. Toxicity of selected organic compounds, part 1.
13. Toxicity of selected organic compounds, part 2.
14. Toxicity of selected organic compounds, part 3.
2. Routes of entry of substances into the human body (absorption, biotransformation, distribution process). Overview of the effects of poisons in the body. Acute and chronic effects of poisons in the body. General principles of treatment of poisoning. Toxicology versus other technical fields.
3. Explanation of important basic concepts in toxicology. The mechanism of effect of toxic substances, factors influencing the effects of toxic substances (including membrane entry). Interaction of toxic substances in the body.
4. Metabolism and disposal of toxins in the human body, first aid for acute poisoning, the treatment of chronic poisoning. Preventive protection against exposure to toxic and harmful substances.
5. Teratogenicity, mutagenicity, carcinogenicity of toxic substances, explanation of the organism-xenobiotic relationship.
6. The influence of the environment on toxicity, external influences, determination of toxicity for unknown substances. Influence of nanosubstances on toxicity (perspectives-advantages and disadvantages).
7. Valid legislation relating to toxic and harmful to health substances. Legislation Law: Corrigendum to Regulation (EC) No. 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures, regulation GHS, Law No. 61/2014 Coll.
8. Classification and coding of toxicological properties and hazards of chemical substances and preparations. (H, P sentences, signal words, etc.).
9. Toxicity of selected elements and inorganic compounds, part 1.
10. Toxicity of selected elements and inorganic compounds, part 2.
11. Toxicity of selected elements and inorganic compounds, part 3.
12. Toxicity of selected organic compounds, part 1.
13. Toxicity of selected organic compounds, part 2.
14. Toxicity of selected organic compounds, part 3.