| Course Unit Code | 450-4031/01 |
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| Number of ECTS Credits Allocated | 4 ECTS credits |
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| Type of Course Unit * | Optional |
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| Level of Course Unit * | Second Cycle |
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| Year of Study * | |
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| Semester when the Course Unit is delivered | Summer Semester |
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| Mode of Delivery | Face-to-face |
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| Language of Instruction | Czech |
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| Prerequisites and Co-Requisites | Course succeeds to compulsory courses of previous semester |
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| Name of Lecturer(s) | Personal ID | Name |
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| AUG011 | prof. Ing. Martin Augustynek, Ph.D. |
| VON0045 | Ing. Jaroslav Vondrák, Ph.D. |
| Summary |
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The aim of this object is study principle of genesis, transfer, processing and retention information in vital systems. As well as modeling and simulation of biological systems. Their study of control method on physiological and pathological terms.
The basis forms a cell, biological membrans, biothermodynamic and biophysical chemistry. The study of biological systems features is orientaited on neurophysiologie, neurological, respiratory, locomotive and vascular systems, heart action, genetical information, sensoric systems and compensation of organ functions.
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| Learning Outcomes of the Course Unit |
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The student aquired during this course information about the origin of genesis, transformation , evaluation and presevation of information in live systems. As well as modeling and simulation of biological systems. Their study of control method on physiological and pathological terms.
The object with its elignment fits into branch of measurements and control techniques in biomedicine. The aquiered knowledge and skill creates the basic knowledge of biomedicine engineering. |
| Course Contents |
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Lectures:
Physiological principles. Energy and life processes. Structure organisms in live nature. Cell, microscopic and submicroscopic structure. Fundamental processes
biological membrane I., Structure and function. Chemical potential. Equilibrium condition in heterogeneous system
biological membrane II., Diaphragmal ionic channels. Transmitter systems for transport ion over membrane
Biotermodynamic I., Introduction into thermodynamic. Thermodynamic of live system, entropy
Biotermodynamic II., Structural thermodynamic. Thermodynamic biological evolution
Neurophysiology - Nervous system. Conveyance and working information in biological system. Nervous, hormonal and humoral level their steerage. Structure of the nervous system, chances of steerage on single level. Central system nervous. Nervous fibre, substitution diagram and quadratic diffusion shock
Genic information. Transmission genic information abreast bioinformatics macromolecule.
Heart. Activity heart and meaning regulation gadgetry at stress
Blood-vessel system. Meaning blood-vessel bed for circulation, chances of and meaning his regulation.
Breathing system. Steerage activities breathing system. Capacity as pulmonary and her regulation in extreme conditions
Kinetic syste. Structure among electric irritation and mechanical responses of muscular cell. Biomechanics of kinetic system
Sensorial systems. Physiochemical principles sensuous sensation. Forms, mechanism. sensorical capacity as of the nervous system. Biological tenet sensuous sensation and chances of his erosion
Organ compensations. Compensation and support capacity as viscus. Compensation capacity as kidneys, heart and pulmonary. External stimulator and implanting
Exercises:
Fundamental constructs, setting account from revolting literature
Laboratories:
Transport mechanism of matters over biological membrane. Illustrative instance. Setting semestral work.
Membrans tension and diaphragmal currents, method metering and analyses.
Simulation chemical and biological action.
Fundamental thermodynamic of biological phenomenon, application structural thermodynamic. Instance of backward bindings in organism with demonstration of their meaning for physiological activity.
Visitation at medical psychology. Psychological test with evaluation and demonstration methodist and medical psychology. Test A.
Visitation of laboratory with demonstration frame of transmission genic information. Genetics man.
Demonstration of endurance test in functional laboratory Cardiopulmunal diagnostics. Demonstration of gadgetry regulation , response affecting circulation on physical stress.
Objectivism as well perfused circumference limbs by the help of laser fotoplethysmography with demonstration changes blood flow depending on changes outdoor environment (cold, warmth).
Demonstration of investigation capacity as pulmonary and changes quiescent ventilation of the lungs on choice outer stimuli.
Visitation on technical orthopaedic. Myoelectric prosthodontics, metering muscular potential.
Demonstration acoustic percept and his sensation, regulation and quantifier. Recite engaged account.
Hemodyalisys, hemofitration, homeoperfusion. Extra-corporeal circulation of blood. Insulindosing machine. Cardiostimulation and defibrillation. Test B.
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| Recommended or Required Reading |
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| Required Reading: |
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[1] Biomedical modeling and simulation on a pc: a workbench. S.l.: Springer, 2012. ISBN 9781461391654.
[2] MEURS, Willem van. Modeling and simulation in biomedical engineering: applications in cardiorespiratory physiology. 1. New York: McGraw-Hill, c2011. ISBN 978-0071714457.
[3] CHRISTOPOULOS, Arthur. Biomedical applications of computer modeling. Boca Raton: CRC Press, c2001. Pharmacology & toxicology (Boca Raton, Fla.). ISBN 9780849301001.
[4] KITTNAR, Otomar a Mikuláš MLČEK. Atlas fyziologických regulací: 329 schémat. Praha: Grada, 2009, 316 s. ISBN 978-80-247-2722-6.
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[1] Biomedical modeling and simulation on a pc: a workbench. S.l.: Springer, 2012. ISBN 9781461391654.
[2] MEURS, Willem van. Modeling and simulation in biomedical engineering: applications in cardiorespiratory physiology. 1. New York: McGraw-Hill, c2011. ISBN 978-0071714457.
[3] CHRISTOPOULOS, Arthur. Biomedical applications of computer modeling. Boca Raton: CRC Press, c2001. Pharmacology & toxicology (Boca Raton, Fla.). ISBN 9780849301001.
[4] KITTNAR, Otomar a Mikuláš MLČEK. Atlas fyziologických regulací: 329 schémat. Praha: Grada, 2009, 316 s. ISBN 978-80-247-2722-6.
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| Recommended Reading: |
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Tiefenbach,P: Biocybernetics,Sylabus on WWW pages of department,2002.
Penhaker,M: Biocybernetics,Sylabus on WWW pages of department,2002.
Samson Wright: Klinická fyziologie Praha 1987.
Stefan Silbernagl, Agamemnom Despopoulos: Atlas fyziologie člověka. Praha 1984.
Wiliam F. Canong: Přehled lékařské fyziologie. Praha 1976.
Hrazdíra, I.: Biofyzika. Praha, Avicenum 1990.
Nečas, O.: Biologie. Praha, Avicenum 1982.
Dvořák - Maršík - Andrej: Biotermodynamika. Praha, Akademia, 1985.
Babloyantz, A.: Molecules, dynamics and life, J.Wiley, New York, 1986.
Talbot, S.a.: Systems physiology, J.Wiley, New York 1973. |
Tiefenbach,P: Biokybernetika, Sylaby na WWW stránkách katedry, 2002,
Penhaker,M: Biokybernetika, Sylaby na WWW stránkách katedry, 2002,
Samson Wright: Klinická fyziologie Praha 1987.
Stefan Silbernagl, Agamemnom Despopoulos: Atlas fyziologie člověka. Praha 1984.
Wiliam F. Canong: Přehled lékařské fyziologie. Praha 1976.
Hrazdíra, I.: Biofyzika. Praha, Avicenum 1990.
Nečas, O.: Biologie. Praha, Avicenum 1982.
Dvořák - Maršík - Andrej: Biotermodynamika. Praha, Akademia, 1985.
Babloyantz, A.: Molecules, dynamics and life, J.Wiley, New York, 1986.
Talbot, S.a.: Systems physiology, J.Wiley, New York 1973. |
| Planned learning activities and teaching methods |
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| Lectures, Individual consultations, Tutorials, Other activities |
| Assesment methods and criteria |
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| Task Title | Task Type | Maximum Number of Points
(Act. for Subtasks) | Minimum Number of Points for Task Passing |
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| Graded credit | Graded credit | 100 (100) | 51 |
| Semestral project | Semestral project | 40 | 20 |
| Test | Written test | 60 | 31 |