| Course Unit Code | 617-0016/05 |
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| Number of ECTS Credits Allocated | 5 ECTS credits |
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| Type of Course Unit * | Choice-compulsory |
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| Level of Course Unit * | First Cycle |
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| Year of Study * | Second Year |
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| Semester when the Course Unit is delivered | Winter Semester |
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| Mode of Delivery | Face-to-face |
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| Language of Instruction | Czech |
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| Prerequisites and Co-Requisites | Course succeeds to compulsory courses of previous semester |
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| Name of Lecturer(s) | Personal ID | Name |
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| KUL37 | doc. Ing. Lenka Kulhánková, Ph.D. |
| Summary |
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Introductory course of organic chemistry covers lessons on the bonds in
organic compounds, structure and basic reactions. Description of basic classes of the organic compounds follows (including the physical properties,
technological and biochemical issues, toxicity, and environmental risk).
Lectures on biochemistry are devoted to the chemistry of living organisms,
metabolc path and its regulation.
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| Learning Outcomes of the Course Unit |
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| The aim of the lectures is creation of basic knowledge of chemical constitution of substances in living organisms, their structure and metabolism. |
| Course Contents |
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1. Lecture:
Introduction into the organic chemistry. History of organic chemistry. Bonding properties of carbon. Intermolecular interaction. Principles of stereochemistry of organic compounds. Drawing organic molecules. Polymerism and isomerism.
Seminary:
Bonding properties of carbon. Inference of molecular, rational and structural formula. Determination of isomerism type in the specific compounds.
2. Lecture:
Chemical reactions of organic compounds. Ranking of organic reactions. Homolysis and heterolysis. Electrophilic and nucleophilic agents. Aliphatic, alicyclic, saturated and unsaturated hydrocarbons. Nomenclature of hydrocarbons. Physical properties, important reactions and application.
Seminary:
Nomenclature of organic compounds.
3. Lecture:
Aromatic compounds. Delocalization of electrons. Physical properties, toxicity, application and important reactions. Derivatives of hydrocarbons. Derivatives of halogens. Physical properties, toxicity, application and important reactions.
Seminary:
Nomenclature of organic compounds.
4. Lecture:
Derivatives of sulfure (thioalcohols and thiophenols, sulphides, sulfonic acids). Physical properties, application and important reactions. Derivatives of nitrogen (nitrocompounds, amines, diazonium salts, azocompounds). Physical properties, toxicity, application and important reactions.
Seminary:
Nomenclature of organic compounds.
5. Lecture:
Derivatives of oxygen (alcohols, phenols, ethers). Physical properties, toxicity, application and important reactions. Carbonyl compounds (aldehydes and ketones). Physical properties, toxicity, application and important reactions.
Seminary:
Nomenclature of organic compounds.
6. Lecture:
Carboxylic acids. Physical properties, application and important reactions.
Seminary:
Nomenclature of organic compounds
7. Lecture:
Derivatives of carboxylic acids. Physical properties, application and important reactions.
Experimental work in lab:
Preparing of fumaric acid.
8. Lecture:
Introduction into the biochemistry. Characterization of living organisms.
Experimental work in lab:
Preparing of jodoform.
9. Lecture:
Amino-acids (structure and properties). Peptides (structure and properties). Proteins (structure and properties).
Experimental work in lab:
Preparing of acetylsalicyclic acid.
10. Lecture:
Saccharides (monosaccharides, glycosides, oligosaccharides and polysaccharides).
Experimental work in lab:
Saccharides.
11. Lecture:
Lipids (characterization and structuring lipids). Terpenes. Steroids.
Experimental work in lab:
Extraction of essential oils.
12. Lecture:
Biotechnology. Detergents.
Experimental work in lab:
Separation of leaf days.
13. Lecture:
Alkaloids (properties and structuring alkaloids).
Experimental work in lab:
Alkaloids and tanstuffs.
14. Lecture:
Enzymes (classification, constitution and molecular properties of enzymes).
Seminary:
Presentation of seminar papers.
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| Recommended or Required Reading |
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| Required Reading: |
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1) McMurry, J. Organic chemistry - 6th ed. - Belmont: Thomson Brooks/Cole, 2004, ISBN 0-534-38999-6.
2) Karlson, P. Biochemistry. 4th edition -Academic Press New York, 1975, ISBN 0123997313
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1) McMurry, J. Organická chemie. VUT Brno 2007, ISBN 978-80-214-3291-8, VUTIUM VŠCHT Praha 2007 ISBN 978-80-7080-637-1.
2) Karlson, P. Základy biochemie. 3. přeprac. vyd. Praha: Academia, 1981, ISBN 104-21-852.
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| Recommended Reading: |
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| Recommended English literature will be selected on the basis of individual consultations. |
1) Červinka, O., Dědek, V., Ferles, M. Organická chemie. Informatorium Praha 1991.
2) Svoboda, J. a spol. Organická chemie I. VŠCHT Praha 2005, ISBN 80-7080-561-7.
3) Waisser, K. Nové české názvosloví organické chemie. Učební texty UK Praha 2002.
4) Fikr, J., Kahovec, J. Názvosloví organické chemie. Rubico, Olomouc, 2002.
5) Doubrava, J., Koštíř, J., Pospíšil, J. Základy biochemie. 1. vyd. Praha: SPN, 1984. ISBN 14-417-74.
6) Klouda, P. Základy biochemie. 1. vyd. Ostrava: Pavel Klouda, 2000. ISBN 80-86369-00-5.
7) Vodrážka, Z. Biochemie. Praha: Academia, 2002. ISBN 80-200-0600-1.
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| Planned learning activities and teaching methods |
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| Lectures, Seminars |
| Assesment methods and criteria |
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| Task Title | Task Type | Maximum Number of Points
(Act. for Subtasks) | Minimum Number of Points for Task Passing |
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| Exercises evaluation and Examination | Credit and Examination | 100 (100) | 51 |
| Exercises evaluation | Credit | 30 (30) | 16 |
| Written | Written test | 30 | 16 |
| Examination | Examination | 70 (70) | 35 |
| Written examination | Written examination | 40 | 21 |
| Oral | Oral examination | 30 | 14 |