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* Exchange students do not have to consider this information when selecting suitable courses for an exchange stay.

Course Unit Code546-0686/04
Number of ECTS Credits Allocated5 ECTS credits
Type of Course Unit *Choice-compulsory type B
Level of Course Unit *Second Cycle
Year of Study *Second Year
Semester when the Course Unit is deliveredWinter Semester
Mode of DeliveryFace-to-face
Language of InstructionCzech
Prerequisites and Co-Requisites Course succeeds to compulsory courses of previous semester
Name of Lecturer(s)Personal IDName
PIK012Mgr. Kristina Čabanová, Ph.D.
The course provides a general overview of issues hydrotoxicology - toxic effects of substances on living organisms and the environment, methods and principles of test, monitoring, interpretation of results and performance evaluation.
-Basic Resources of the biosphere
-Effects Toxic substances on organisms in general and flora
-Toxicita Various organic and inorganic substances and compounds
-Toxicita Treatment, industrial and agricultural
-The factors affecting toxicity
-Biologic Methods for assessing the potential effects of pollutants
-Bioindication Feature fish
-Information hydrotoxicologic systems and their applications, new trends, techniques and tendencies - enzymatic methods, genotoxicity, QSAR.
Learning Outcomes of the Course Unit
The object provides view of problems toxic matters attack on organisms and flora generally.
Course Contents
1. Basic resources of the biosphere, their relationship and the importance of ecology flora and fauna the aquatic environment. History, development, concepts, definitions and divisions of Toxicology, the application.
2. The effects of toxic substances on organisms and flora in general, specific and potential effects related to requirements for water quality according to the methods of water use.
3. Toxicity of various organic and inorganic substances and compounds,
Toxicity of heavy metals and radioactive substances, nitrogen compounds, chlorinated hydrocarbons, acids chlorophenoxyacetic, organophosphates, carbonates, pesticides and detergents.
4. Toxicity of treatment, industrial and agricultural - from pulp and paper mills, textile dyes, industrial auxiliary agents, ap. Toxic metabolites produced microorganisms, bacterial toxins, mycotoxins.
5. Factors affecting toxicity (properties of water, the sensitivity of organisms present incidence of various substances, etc.) and biodegradability tests of biodegradability, standards.
6. - 7. Determination of toxicity - the main toxicological values​​, methods and procedures establish principles and implementation, the choice of methods and test organisms.
8. - 9. Biological methods for assessment of the potential effects of pollutants, the use of an application of test results - hydrotoxicity assessment methods, risk, effectiveness of treatment technology and water treatment, the risk of wastewater extracts.
10. - 11. Bioindication features fish, freshwater fish contaminants load
(presence of heavy metals in fish muscle, histological - pathological changes, etc.), changes in the composition of fish communities in emergency and permanent changes quality water, the correlation between the health status of fish and toxicity.
12. Evaluation experiments (orthogonal polynomials, use of experimental comparing the results of different tests, quality assessment water by toxicity tests (risk treatment efficiency), the relationship of toxicity tests and chemical analysis.
13. Information hydrotoxicology systems and their applications, model situations and their solutions. Current status of surface flows in terms of toxicity. New trends, practices and trends - enzymatic methods, etc.

Experimental character - hydrotoxicology tests.
Recommended or Required Reading
Required Reading:
HODGSON Ernest ed.: A Textbook of Modern Toxicology. Third edition, A JOHN WILEY & SONS, INC., PUBLICATION, 2004. 582 p. dostupné z:,%203rd%20ed%202004(2).pdf.
KOMÍNKOVÁ, Dana. Ekotoxikologie. V Praze: České vysoké učení technické, 2011dotisk. ISBN 978-80-01-04058-4.
ANDĚL, Petr. Ekotoxikologie, bioindikace a biomonitoring. Liberec: Evernia, 2011. ISBN 978-80-903787-9-7.
PROKEŠ, Jaroslav. Základy toxikologie: obecná toxikologie a ekotoxikologie. Praha: Karolinum, c2005. Základy. ISBN 80-7262-301-X.
OSTRANDER, Gary K. (ed.). Techniques in aquatic toxicology. CRC Press, 2005.
Recommended Reading:
NORDBERG Gunnar F., BRUCE A. FOWLER Monica Nordberg, LARS Friberg (Ed): Handbook on the Toxicology of Metals 3rd Edition. Elsevier 2007. 998 p. ISBN: 978-0-12-369413-3. Dostupné z:,%20et%20al.,%20(AP,%202007)%20WW.pdf
LINHART Igor: Toxikologie, 2. upravené a rozšířené vydání, VŠCHT PRAHA, 2014. 410 s. ISBN 978-80-7080-877-1.
KOČÍ, Vladimír a Klára MOCOVÁ. Ekotoxikologie pro chemiky. Praha: Vysoká škola chemicko-technologická v Praze, 2009. ISBN 978-80-7080-699-9.
LABBATE, Maurizio, et al. Anthropogenic impacts on the microbial ecology and function of aquatic environments. Frontiers in microbiology, 2016.
HODGSON Ernest ed.: A Textbook of Modern Toxicology. Third edition, A JOHN WILEY & SONS, INC., PUBLICATION, 2004. 582 p. dostupné z:,%203rd%20ed%202004(2).pdf.
Planned learning activities and teaching methods
Lectures, Experimental work in labs, Project work, Other activities
Assesment methods and criteria
Task TitleTask TypeMaximum Number of Points
(Act. for Subtasks)
Minimum Number of Points for Task Passing
Credit and ExaminationCredit and Examination100 (100)51
        CreditCredit33 18
        ExaminationExamination67 (67)33
                Písemná zkouškaWritten examination30 18
                Ústní zkouškaOral examination37 15